Florida Memorial University will award a posthumous degree to Trayvon Martin, five years after the black teen was shot dead by a neighbourhood watchman.
The teen’s parents will accept a degree in aeronautical science on his behalf on 13 May.
The university said it wants to honour the 17-year-old’s ambition to become a pilot before he died in 2012.
His death prompted nationwide protests and a fierce debate about race relations in the US.
The unarmed black teenager was walking home from a shop in Sanford, Florida, when he got into an altercation with George Zimmerman, a white neighbourhood watch volunteer.
Mr Zimmerman, 29, argued he acted in self-defence and with justifiable use of deadly force.
A jury acquitted Mr Zimmerman of second-degree murder in 2013.
Following the verdict, protests erupted in cities across the US including Philadelphia, Chicago, San Francisco, Washington and Atlanta.
The case was instrumental in launching the national Black Live Matter social movement.
Sybrina Fulton and Tracy Martin, the teen’s parents will accept the degree in Miami Gardens, where Ms Fulton went to school.
Roslyn Clark, the university’s president, said in a Facebook post the school was honouring Mr Martin for “his long dream and the steps he took during his young life toward becoming a pilot”.
“Sybrina, our alum, epitomises strength and dignity as she uplifts other victims of violence while effecting change for a more equal and just society,” she added.
Ms Fulton said she was “grateful” for her son’s honorary degree.
“In 1997 I graduated from FMU with a Bachelors degree in English with a minor in Mass Communications. It’s now 20 years later & now my son #TrayvonMartin will receive his Bachelors in Aviation, something he loved,” she said in a Facebook post.
Trayvon Martin to receive honorary college degree